6P69: Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to compound 11

PDB ID: 6P69Download
MMDB ID: 176612
PDB Deposition Date: 2019/6/3
Updated in MMDB: 2019/07
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6P69: monomeric; determined by author
Molecular Components in 6P69
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 1
(Gene symbol: FGFR1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
SULFATE IONSULFATE ION
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamideN-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303