6P4V: 1.65 Angstrom ternary complex of Deoxyhypusine synthase with cofactor NAD and spermidine mimic inhibitor GC7

PDB ID: 6P4VDownload
MMDB ID: 185884
PDB Deposition Date: 2019/5/28
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6P4V: tetrameric; determined by author and by software (PISA)
Molecular Components in 6P4V
Label Count Molecule
Proteins (4 molecules)
4
Deoxyhypusine Synthase
(Gene symbol: DHPS)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
1-GUANIDINIUM-7-AMINOHEPTANE1-GUANIDINIUM-7-AMINOHEPTANE
3
2
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303