6P1P: Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming dCMPNPP

PDB ID: 6P1PDownload
MMDB ID: 179126
PDB Deposition Date: 2019/5/20
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 6P1P: tetrameric; determined by author and by software (PISA)
Molecular Components in 6P1P
Label Count Molecule
Protein (1 molecule)
1
DNA-directed Dna/rna Polymerase MU
(Gene symbol: POLM)
Molecule annotation
Nucleotides(3 molecules)
1
DNA (5'-d(*cp*gp*gp*cp*(8og)p*tp*ap*cp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*gp*tp*a)-3')
Molecule annotation
1
DNA (5'-d(p*gp*cp*cp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
SODIUM IONSODIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303