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6P0B:
Human DNA Ligase 1 (E346A/E592A) Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+
PDB ID:
6P0B
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MMDB ID:
182123
PDB Deposition Date:
2019/5/16
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
2.203 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
B, C, D
Homo sapiens
A
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6P0B: tetrameric; determined by author and by software (PISA)
Molecular Components in 6P0B
Label
Count
Molecule
Protein (1 molecule)
A
1
DNA Ligase 1
Nucleotides(3 molecules)
B
1
DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*tp*c)-3')
C
1
DNA (5'-d(p*gp*tp*cp*gp*gp*ap*c)-3')
D
1
DNA (5'-d(*gp*tp*cp*cp*gp*ap*cp*gp*ap*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM ION
2
1
DI(HYDROXYETHYL)ETHER
3
1
ADENOSINE MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303