6OYT: ASK1 kinase domain in complex with GS-4997

PDB ID: 6OYTDownload
MMDB ID: 181724
PDB Deposition Date: 2019/5/15
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.824  Å
Source Organism:
Similar Structures:
Biological Unit for 6OYT: dimeric; determined by author and by software (PISA)
Molecular Components in 6OYT
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase 5
(Gene symbol: MAP3K5)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide
2
3
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303