6OTZ: Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (+)FTC-TP

PDB ID: 6OTZDownload
MMDB ID: 177762
PDB Deposition Date: 2019/5/3
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.857  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6OTZ: tetrameric; determined by author and by software (PISA)
Molecular Components in 6OTZ
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
Molecule annotation
Nucleotides(2 molecules)
1
DNA Primer 20-mer
Molecule annotation
1
DNA Template 27-mer
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
SULFATE IONSULFATE ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
[[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate[[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303