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6OTG:
HIV-1 protease triple mutants V32I, I47V, V82I with GRL-011-11A (a methylamine bis-Tetrahydrofuran P2-Ligand, sulfonamide isostere derivate)
PDB ID:
6OTG
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MMDB ID:
175894
PDB Deposition Date:
2019/5/3
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
1.5 Å
Source Organism:
Human immunodeficiency virus 1
Similar Structures:
VAST+
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Biological Unit for 6OTG: dimeric; determined by author and by software (PISA)
Molecular Components in 6OTG
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Protease
Chemicals and Non-standard biopolymers (6 molecules)
1
4
FORMIC ACID
2
1
(3R,3aS,4R,6aR)-4-(methylamino)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate
3
1
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303