6ORV: Non-peptide agonist (TT-OAD2) bound to the Glucagon-Like peptide-1 (GLP-1) Receptor

PDB ID: 6ORVDownload
MMDB ID: 192597
PDB Deposition Date: 2019/5/1
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 6ORV: pentameric; determined by author
Molecular Components in 6ORV
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
(Gene symbol: GNAS)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Nanobody 35
Molecule annotation
1
Glucagon-like Peptide 1 Receptor
(Gene symbol: GLP1R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{(3S,8S)-3-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl}-4-(2,3-dimethylpyridin-4-yl)-L-phenylalanineN-{(3S,8S)-3-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl}-4-(2,3-dimethylpyridin-4-yl)-L-phenylalanine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303