6OPT: HIV-1 Protease NL4-3 V82F, I84V Mutant in complex with darunavir

PDB ID: 6OPTDownload
MMDB ID: 179099
PDB Deposition Date: 2019/4/25
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6OPT: dimeric; determined by author and by software (PISA)
Molecular Components in 6OPT
Label Count Molecule
Proteins (2 molecules)
2
Protease Nl4-3
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303