6OOT: HIV-1 Protease NL4-3 L89V, L90M Mutant in complex with darunavir

PDB ID: 6OOTDownload
MMDB ID: 178679
PDB Deposition Date: 2019/4/23
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.822  Å
Source Organism:
Similar Structures:
Biological Unit for 6OOT: dimeric; determined by author and by software (PISA)
Molecular Components in 6OOT
Label Count Molecule
Proteins (2 molecules)
2
Nl4-3 Protease
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SULFATE IONSULFATE ION
2
1
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303