6OOB: Human CYP3A4 bound to a suicide substrate

PDB ID: 6OOBDownload
MMDB ID: 179335
PDB Deposition Date: 2019/4/22
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.202  Å
Source Organism:
Similar Structures:
Biological Unit for 6OOB: tetrameric; determined by software (PISA)
Molecular Components in 6OOB
Label Count Molecule
Proteins (4 molecules)
4
Cytochrome P450 3A4
(Gene symbol: CYP3A4)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
4-{[(2Z,6S)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one4-{[(2Z,6S)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303