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6OO9:
Human CYP3A4 bound to a drug mibefradil
PDB ID:
6OO9
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MMDB ID:
179333
PDB Deposition Date:
2019/4/22
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
2.25 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6OO9: tetrameric; determined by software (PISA)
Molecular Components in 6OO9
Label
Count
Molecule
Proteins (4 molecules)
A
A_1
A_2
A_3
4
Cytochrome P450 3A4
(Gene symbol:
CYP3A4
)
Chemicals and Non-standard biopolymers (20 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FE
2
4
(1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate
3
8
1,2-ETHANEDIOL
4
4
DIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303