6OCW: Crystal Structure of Mycobacterium tuberculosis Proteasome in Complex with Phenylimidazole-based Inhibitor A85

PDB ID: 6OCWDownload
MMDB ID: 180305
PDB Deposition Date: 2019/3/25
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6OCW: 28-meric; determined by author and by software (PISA)
Molecular Components in 6OCW
Label Count Molecule
Proteins (28 molecules)
14
Proteasome Subunit Alpha
(Gene symbol: prcA)
Molecule annotation
14
Proteasome Subunit Beta
(Gene symbol: prcB)
Molecule annotation
Chemicals and Non-standard biopolymers (43 molecules)
1
15
DIMETHYLFORMAMIDEDIMETHYLFORMAMIDE
2
14
N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-4-[(2S)-2-methylpiperidin-1-yl]-1,4-dioxobutan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name)N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-4-[(2S)-2-methylpiperidin-1-yl]-1,4-dioxobutan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name)
3
14
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303