6O3I: Crystal Structure of Human IDO1 bound to navoximod (NLG-919)

PDB ID: 6O3IDownload
MMDB ID: 177517
PDB Deposition Date: 2019/2/26
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 6O3I: monomeric; determined by author and by software (PISA)
Molecular Components in 6O3I
Label Count Molecule
Protein (1 molecule)
1
Indoleamine 2,3-dioxygenase 1
(Gene symbol: IDO1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
trans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-oltrans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303