6O0H: Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143

PDB ID: 6O0HDownload
MMDB ID: 174440
PDB Deposition Date: 2019/2/16
Updated in MMDB: 2019/05
Experimental Method:
electron microscopy
Resolution: 3.67  Å
Source Organism:
Similar Structures:
Biological Unit for 6O0H: tetrameric; determined by author
Molecular Components in 6O0H
Label Count Molecule
Proteins (4 molecules)
4
Atp-citrate Synthase
(Gene symbol: ACLY)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoatemethyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
2
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303