NCBI
National Center for
Biotechnology Information
Search
6O0H:
Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
PDB ID:
6O0H
Download
MMDB ID:
174440
PDB Deposition Date:
2019/2/16
Updated in MMDB:
2019/05
Experimental Method:
electron microscopy
Resolution:
3.67 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6O0H: tetrameric; determined by author
Molecular Components in 6O0H
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Atp-citrate Synthase
(Gene symbol:
ACLY
)
Chemicals and Non-standard biopolymers (8 molecules)
1
4
methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
2
4
ADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303