6O0G: M.tb MenD bound to Intermediate I and Inhibitor

PDB ID: 6O0GDownload
MMDB ID: 184296
PDB Deposition Date: 2019/2/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6O0G: tetrameric; determined by author and by software (PISA)
Molecular Components in 6O0G
Label Count Molecule
Proteins (4 molecules)
4
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate Synthase
(Gene symbol: menD)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
4
1,4-dihydroxy-2-naphthoic acid1,4-dihydroxy-2-naphthoic acid
2
4
ACETATE IONACETATE ION
3
8
FORMIC ACIDFORMIC ACID
4
1
2-OXOGLUTARIC ACID2-OXOGLUTARIC ACID
5
2
4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid
6
2
MAGNESIUM IONMAGNESIUM ION
7
1
CHLORIDE IONCHLORIDE ION
8
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
9
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303