6NWL: Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with hydrocortisone and PGC1a coregulator fragment

PDB ID: 6NWLDownload
MMDB ID: 180688
PDB Deposition Date: 2019/2/6
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.595  Å
Source Organism:
Similar Structures:
Biological Unit for 6NWL: dimeric; determined by author
Molecular Components in 6NWL
Label Count Molecule
Proteins (2 molecules)
1
Glucocorticoid Receptor
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha
(Gene symbol: PPARGC1A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
2
3
GLYCEROLGLYCEROL
3
1
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
4
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
5
2
THIOCYANATE IONTHIOCYANATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303