6NWK: Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with dexamethasone and PGC1a coregulator fragment

PDB ID: 6NWKDownload
MMDB ID: 180687
PDB Deposition Date: 2019/2/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6NWK: dimeric; determined by author and by software (PISA)
Molecular Components in 6NWK
Label Count Molecule
Proteins (2 molecules)
1
Glucocorticoid Receptor
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha
(Gene symbol: PPARGC1A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
DEXAMETHASONEDEXAMETHASONE
2
1
FORMIC ACIDFORMIC ACID
3
1
ACETYL GROUPACETYL GROUP
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303