6NV2: 14-3-3 sigma with RelA/p65 binding site pS45 in complex with DP005

PDB ID: 6NV2Download
MMDB ID: 187451
PDB Deposition Date: 2019/2/4
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.13  Å
Source Organism:
Similar Structures:
Biological Unit for 6NV2: tetrameric; determined by author and by software (PISA)
Molecular Components in 6NV2
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Transcription Factor P65
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
(4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside(4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303