6NTN: Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-230 in Complex with the Reactivator, HI-6

PDB ID: 6NTNDownload
MMDB ID: 189441
PDB Deposition Date: 2019/1/29
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.697  Å
Source Organism:
Similar Structures:
Biological Unit for 6NTN: dimeric; determined by author and by software (PISA)
Molecular Components in 6NTN
Label Count Molecule
Proteins (2 molecules)
2
Acetylcholinesterase
(Gene symbol: ACHE)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
7
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
alpha-L-fucopyranosealpha-L-fucopyranose
3
2
4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM
4
2
(S)-N-[(1E)-1-(diethylamino)ethylidene]-P-methylphosphonamidic fluoride(S)-N-[(1E)-1-(diethylamino)ethylidene]-P-methylphosphonamidic fluoride
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303