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6NT2:
type 1 PRMT in complex with the inhibitor GSK3368715
PDB ID:
6NT2
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MMDB ID:
177289
PDB Deposition Date:
2019/1/28
Updated in MMDB:
2019/07
Experimental Method:
x-ray diffraction
Resolution:
2.48 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6NT2: dimeric; determined by author
Molecular Components in 6NT2
Label
Count
Molecule
Proteins (2 molecules)
A
D
2
Protein Arginine N-methyltransferase 1
(Gene symbol:
PRMT1
)
Chemicals and Non-standard biopolymers (17 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINE
2
2
N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine
3
13
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303