6NP0: Cryo-EM structure of 5HT3A receptor in presence of granisetron

PDB ID: 6NP0Download
MMDB ID: 177720
PDB Deposition Date: 2019/1/17
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.92  Å
Source Organism:
Similar Structures:
Biological Unit for 6NP0: pentameric; determined by author
Molecular Components in 6NP0
Label Count Molecule
Proteins (5 molecules)
5
5-hydroxytryptamine Receptor 3A
(Gene symbol: Htr3a)
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
30
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranosebeta-D-mannopyranose
3
5
1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303