6NHA: Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody

PDB ID: 6NHADownload
MMDB ID: 182571
PDB Deposition Date: 2018/12/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.381  Å
Source Organism:
Similar Structures:
Biological Unit for 6NHA: tetrameric; determined by author and by software (PISA)
Molecular Components in 6NHA
Label Count Molecule
Proteins (4 molecules)
1
IGG Receptor Fcrn Large Subunit P51
(Gene symbol: FCGRT)
Molecule annotation
1
Beta-2-microglobulin
(Gene symbol: B2M)
Molecule annotation
1
Synt001-fab Light Chain
Molecule annotation
1
Synt001-fab Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303