6N79: Structure of the human JAK1 kinase domain with compound 20

PDB ID: 6N79Download
MMDB ID: 174672
PDB Deposition Date: 2018/11/27
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Similar Structures:
Biological Unit for 6N79: monomeric; determined by author and by software (PISA)
Molecular Components in 6N79
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak1
(Gene symbol: JAK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-{5-[5-chloro-2-(difluoromethoxy)phenyl]-1H-pyrazol-4-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamideN-{5-[5-chloro-2-(difluoromethoxy)phenyl]-1H-pyrazol-4-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303