6N48: Structure of beta2 adrenergic receptor bound to BI167107, Nanobody 6B9, and a positive allosteric modulator

PDB ID: 6N48Download
MMDB ID: 176787
PDB Deposition Date: 2018/11/17
Updated in MMDB: 2019/07
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Enterobacteria phage RB59▼
Similar Structures:
Biological Unit for 6N48: dimeric; determined by author and by software (PISA)
Molecular Components in 6N48
Label Count Molecule
Proteins (2 molecules)
1
Endolysin,beta-2 Adrenergic Receptor,beta-2 Adrenergic Receptor Chimera
Molecule annotation
1
Camelid Antibody Fragment
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one
2
1
(2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate(2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate
3
1
N-[(3R)-4-(4-tert-butylphenyl)-3-({2-[(4-methoxyphenyl)sulfanyl]-5-[methyl(propan-2-yl)sulfamoyl]benzene-1-carbonyl}amino)butanoyl]glycineN-[(3R)-4-(4-tert-butylphenyl)-3-({2-[(4-methoxyphenyl)sulfanyl]-5-[methyl(propan-2-yl)sulfamoyl]benzene-1-carbonyl}amino)butanoyl]glycine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303