6MOZ: Structure of acid-beta-glucosidase in complex with an aromatic pyrrolidine iminosugar inhibitor

PDB ID: 6MOZDownload
MMDB ID: 176526
PDB Deposition Date: 2018/10/5
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6MOZ: monomeric; determined by author
Molecular Components in 6MOZ
Label Count Molecule
Protein (1 molecule)
1
Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
1
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
15
SODIUM IONSODIUM ION
3
1
(2R,3S,4R)-2-{[4-(3,5-dichlorophenyl)-1H-1,2,3-triazol-1-yl]methyl}pyrrolidine-3,4-diol(2R,3S,4R)-2-{[4-(3,5-dichlorophenyl)-1H-1,2,3-triazol-1-yl]methyl}pyrrolidine-3,4-diol
4
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303