6M8P: Human ERAP1 bound to phosphinic pseudotripeptide inhibitor DG013

PDB ID: 6M8PDownload
MMDB ID: 190959
PDB Deposition Date: 2018/8/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.31  Å
Source Organism:
Similar Structures:
Biological Unit for 6M8P: monomeric; determined by author
Molecular Components in 6M8P
Label Count Molecule
Protein (1 molecule)
1
Endoplasmic Reticulum Aminopeptidase 1
(Gene symbol: ERAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
ZINC IONZINC ION
3
1
Nalpha-[(2S)-2-{[[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]methyl}-4-methylpentanoyl]-L-tryptophanamideNalpha-[(2S)-2-{[[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]methyl}-4-methylpentanoyl]-L-tryptophanamide
4
16
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303