6M5W: Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid

PDB ID: 6M5WDownload
MMDB ID: 197645
PDB Deposition Date: 2020/3/11
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6M5W: tetrameric; determined by author
Molecular Components in 6M5W
Label Count Molecule
Proteins (4 molecules)
4
Serine Hydroxymethyltransferase, Cytosolic
(Gene symbol: SHMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
4
(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID
3
4
GLYCINEGLYCINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303