6M5O: Co-crystal structure of human serine hydroxymethyltransferase 2 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid

PDB ID: 6M5ODownload
MMDB ID: 197642
PDB Deposition Date: 2020/3/11
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.30001  Å
Source Organism:
Similar Structures:
Biological Unit for 6M5O: dimeric; determined by author and by software (PISA)
Molecular Components in 6M5O
Label Count Molecule
Proteins (2 molecules)
2
Serine Hydroxymethyltransferase, Mitochondrial
(Gene symbol: SHMT2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID
2
2
GLYCINEGLYCINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303