6M38: X-ray structure of a Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in S-duloxetine bound form

PDB ID: 6M38Download
MMDB ID: 198736
PDB Deposition Date: 2020/3/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.001  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6M38: trimeric; determined by author
Molecular Components in 6M38
Label Count Molecule
Proteins (3 molecules)
1
Sodium-dependent Dopamine Transporter
Molecule annotation
1
Antibody Fragment 9D5 Light Chain
Molecule annotation
1
Antibody Fragment 9D5 Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
(3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine(3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
2
1
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
3
2
SODIUM IONSODIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
1
DECYL-BETA-D-MALTOPYRANOSIDEDECYL-BETA-D-MALTOPYRANOSIDE
6
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303