6M2W: Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL)

PDB ID: 6M2WDownload
MMDB ID: 191868
PDB Deposition Date: 2020/3/1
Updated in MMDB: 2020/09
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Oryctolagus cuniculus▼
Similar Structures:
Biological Unit for 6M2W: dodecameric; determined by author
Molecular Components in 6M2W
Label Count Molecule
Proteins (12 molecules)
4
Ryanodine Receptor 1,ryanodine Receptor 1,ryanodine Receptor 1,ryanodine Receptor 1,ryanodine Receptor 1,ryanodine Receptor 1,ryanodine Receptor 1
Molecule annotation
4
Peptidyl-prolyl Cis-trans Isomerase Fkbp1b
Molecule annotation
4
Calmodulin-1
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
4
CAFFEINECAFFEINE
2
4
CALCIUM IONCALCIUM ION
3
4
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
4
ZINC IONZINC ION
5
4
5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303