6M07: Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor

PDB ID: 6M07Download
MMDB ID: 196918
PDB Deposition Date: 2020/2/20
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.64  Å
Source Organism:
Similar Structures:
Biological Unit for 6M07: monomeric; determined by author
Molecular Components in 6M07
Label Count Molecule
Protein (1 molecule)
1
Platelet-activating Factor Acetylhydrolase
(Gene symbol: PLA2G7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-2-[(E)-3-[2-(diethylamino)ethyl-[[4-[4-(trifluoromethyl)-2-[2,2,2-tris(fluoranyl)ethoxy]phenyl]phenyl]methyl]amino]-1-oxidanyl-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid(2S)-2-[(E)-3-[2-(diethylamino)ethyl-[[4-[4-(trifluoromethyl)-2-[2,2,2-tris(fluoranyl)ethoxy]phenyl]phenyl]methyl]amino]-1-oxidanyl-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303