6LZE: The crystal structure of COVID-19 main protease in complex with an inhibitor 11a

PDB ID: 6LZEDownload
MMDB ID: 186952
PDB Deposition Date: 2020/2/19
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.505  Å
Source Organism:
Similar Structures:
Biological Unit for 6LZE: tetrameric; determined by author and by software (PISA)
Molecular Components in 6LZE
Label Count Molecule
Proteins (2 molecules)
2
3c-like Proteinase
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
DD_1
2
ICB-ALC-ELL
1
8
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
2
~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303