6LW1: Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form

PDB ID: 6LW1Download
MMDB ID: 195030
PDB Deposition Date: 2020/2/6
Updated in MMDB: 2020/12
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6LW1: dimeric; determined by author
Molecular Components in 6LW1
Label Count Molecule
Proteins (2 molecules)
2
Toll-like Receptor 7
(Gene symbol: TLR7)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purine2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303