6LW0: Crystal structure of TLR7/Cpd-6 (DSR-139293) complex

PDB ID: 6LW0Download
MMDB ID: 195029
PDB Deposition Date: 2020/2/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6LW0: dimeric; determined by author and by software (PISA)
Molecular Components in 6LW0
Label Count Molecule
Proteins (2 molecules)
2
Toll-like Receptor 7
(Gene symbol: TLR7)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
12
SULFATE IONSULFATE ION
3
2
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purin-6-amine2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purin-6-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303