6LUQ: Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands

PDB ID: 6LUQDownload
MMDB ID: 184800
PDB Deposition Date: 2020/1/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6LUQ: monomeric; determined by author and by software (PISA)
Molecular Components in 6LUQ
Label Count Molecule
Protein (1 molecule)
1
Chimera of D(2) Dopamine Receptor and Endolysin
(Gene symbol: DRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
2
4
OLEIC ACIDOLEIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303