6LRE: Human cGAS catalytic domain bound with compound 3

PDB ID: 6LREDownload
MMDB ID: 189177
PDB Deposition Date: 2020/1/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 6LRE: dimeric; determined by author
Molecular Components in 6LRE
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ZINC IONZINC ION
2
2
1,3-bis(oxidanylidene)benzo[de]isoquinoline-6,7-dicarboxylic acid1,3-bis(oxidanylidene)benzo[de]isoquinoline-6,7-dicarboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303