6LO2: Crystal structure of EED in complex with EZH2 peptide and compound 11#

PDB ID: 6LO2Download
MMDB ID: 203925
PDB Deposition Date: 2020/1/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.21  Å
Source Organism:
Similar Structures:
Biological Unit for 6LO2: dimeric; determined by author and by software (PISA)
Molecular Components in 6LO2
Label Count Molecule
Proteins (2 molecules)
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
1
Histone-lysine N-methyltransferase Ezh2
(Gene symbol: EZH2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-[4-[(dimethylamino)methyl]phenyl]-N-[(2-methoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-5-amine8-[4-[(dimethylamino)methyl]phenyl]-N-[(2-methoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-5-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303