6LKA: Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds

PDB ID: 6LKADownload
MMDB ID: 188925
PDB Deposition Date: 2019/12/18
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.033  Å
Source Organism:
Similar Structures:
Biological Unit for 6LKA: monomeric; determined by author
Molecular Components in 6LKA
Label Count Molecule
Protein (1 molecule)
1
3C Proteinase
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303