NCBI
National Center for
Biotechnology Information
Search
6KZC:
crystal structure of TRKc in complex with 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-N-(3-((4- methylpiperazin-1-yl)methyl)-5- (trifluoromethyl)phenyl)benzamide
PDB ID:
6KZC
Download
MMDB ID:
180282
PDB Deposition Date:
2019/9/23
Updated in MMDB:
2019/10
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6KZC: monomeric; determined by author
Molecular Components in 6KZC
Label
Count
Molecule
Protein (1 molecule)
A
1
Nt-3 Growth Factor Receptor
(Gene symbol:
NTRK3
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303