6KQI: Structure of an allosteric modulator bound to the CB1 cannabinoid receptor

PDB ID: 6KQIDownload
MMDB ID: 180663
PDB Deposition Date: 2019/8/17
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.245  Å
Source Organism:
Similar Structures:
Biological Unit for 6KQI: monomeric; determined by author
Molecular Components in 6KQI
Label Count Molecule
Protein (1 molecule)
1
Cannabinoid Receptor 1,glga Glycogen Synthase,cannabinoid Receptor 1
(Gene symbol: CNR1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol
2
1
5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide
3
4
OLEIC ACIDOLEIC ACID
4
2
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
5
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303