6KNU: THRb mutation with a novel agonist

PDB ID: 6KNUDownload
MMDB ID: 180659
PDB Deposition Date: 2019/8/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6KNU: dimeric; determined by author and by software (PISA)
Molecular Components in 6KNU
Label Count Molecule
Proteins (2 molecules)
1
Thyroid Hormone Receptor Beta
(Gene symbol: THRB)
Molecule annotation
1
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[(1-methyl-4-oxidanyl-7-phenoxy-isoquinolin-3-yl)carbonylamino]ethanoic acid2-[(1-methyl-4-oxidanyl-7-phenoxy-isoquinolin-3-yl)carbonylamino]ethanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303