6KLA: Crystal structure of human c-KIT kinase domain in complex with compound 15a

PDB ID: 6KLADownload
MMDB ID: 181688
PDB Deposition Date: 2019/7/30
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.109  Å
Source Organism:
Similar Structures:
Biological Unit for 6KLA: dimeric; determined by author and by software (PISA)
Molecular Components in 6KLA
Label Count Molecule
Proteins (2 molecules)
2
Mast/stem Cell Growth Factor Receptor KIT
(Gene symbol: KIT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amineN-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303