6K5O: Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists

PDB ID: 6K5ODownload
MMDB ID: 177697
PDB Deposition Date: 2019/5/29
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 6K5O: dimeric; determined by author and by software (PISA)
Molecular Components in 6K5O
Label Count Molecule
Proteins (2 molecules)
1
Vitamin D3 Receptor
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3-methylsulfonyloxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid(4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3-methylsulfonyloxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303