6K3E: LSD1/Co-Rest structure with an inhibitor

PDB ID: 6K3EDownload
MMDB ID: 239295
PDB Deposition Date: 2019/5/17
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.87  Å
Source Organism:
Similar Structures:
Biological Unit for 6K3E: dimeric; determined by author and by software (PISA)
Molecular Components in 6K3E
Label Count Molecule
Proteins (2 molecules)
1
Lysine-specific Histone Demethylase 1A
(Gene symbol: KDM1A)
Molecule annotation
1
Rest Corepressor 1
(Gene symbol: RCOR1)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
1
piperidin-4-ylmethyl 4-fluoranyl-4-[[[(1~{R},2~{S})-2-phenylcyclopropyl]amino]methyl]piperidine-1-carboxylatepiperidin-4-ylmethyl 4-fluoranyl-4-[[[(1~{R},2~{S})-2-phenylcyclopropyl]amino]methyl]piperidine-1-carboxylate
2
1
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
3
2
ACETATE IONACETATE ION
4
3
MALONIC ACIDMALONIC ACID
5
4
GLYCEROLGLYCEROL
6
1
2-PCPA derivative2-PCPA derivative
7
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
9
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303