6JWY: Crystal structure of Plasmodium falciparum HPPK-DHPS A437G with SDX-DHP

PDB ID: 6JWYDownload
MMDB ID: 184036
PDB Deposition Date: 2019/4/21
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6JWY: dimeric; determined by author and by software (PISA)
Molecular Components in 6JWY
Label Count Molecule
Proteins (2 molecules)
2
7,8-dihydro-6-hydroxymethylpterin Pyrophosphokinase-dihydropteroate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
2
1
2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE
3
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
3
MAGNESIUM IONMAGNESIUM ION
5
1
CALCIUM IONCALCIUM ION
6
5
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303