6JWW: Crystal structure of Plasmodium falciparum HPPK-DHPS S436F/A437G/A613T triple mutant with STZ-DHP

PDB ID: 6JWWDownload
MMDB ID: 184034
PDB Deposition Date: 2019/4/21
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 6JWW: dimeric; determined by author and by software (PISA)
Molecular Components in 6JWW
Label Count Molecule
Proteins (2 molecules)
2
7,8-dihydro-6-hydroxymethylpterin Pyrophosphokinase-dihydropteroate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide
2
1
2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
2
MAGNESIUM IONMAGNESIUM ION
5
4
ACETATE IONACETATE ION
6
2
CALCIUM IONCALCIUM ION
7
1
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303