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6JSF:
Crystal Structure of BACE1 in complex with N-(3-((4S,5S)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide
PDB ID:
6JSF
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MMDB ID:
178874
PDB Deposition Date:
2019/4/8
Updated in MMDB:
2019/08
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6JSF: monomeric; determined by author and by software (PISA)
Molecular Components in 6JSF
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemicals and Non-standard biopolymers (10 molecules)
1
7
IODIDE ION
2
2
DIMETHYL SULFOXIDE
3
1
N-[3-[(4S,5S)-2-azanyl-4-methyl-5-phenyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303