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6JQR:
Crystal structure of FLT3 in complex with gilteritinib
PDB ID:
6JQR
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MMDB ID:
181437
PDB Deposition Date:
2019/4/1
Updated in MMDB:
2019/11
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6JQR: monomeric; determined by author and by software (PISA)
Molecular Components in 6JQR
Label
Count
Molecule
Protein (1 molecule)
A
1
Receptor-type Tyrosine-protein Kinase Flt3,receptor-type Tyrosine-protein Kinase Flt3
(Gene symbol:
FLT3
)
Chemicals and Non-standard biopolymers (8 molecules)
1
1
6-ethyl-3-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
2
3
SULFATE ION
3
3
GLYCEROL
4
1
3-CYCLOHEXYL-1-PROPYLSULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303