6JPE: Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1

PDB ID: 6JPEDownload
MMDB ID: 187154
PDB Deposition Date: 2019/3/26
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.601  Å
Source Organism:
Similar Structures:
Biological Unit for 6JPE: monomeric; determined by author and by software (PISA)
Molecular Components in 6JPE
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 4
(Gene symbol: FGFR4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamideN-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303